Significant new data from the Journal of Experimental Dermatology provides convincing evidence that topical cannabinoids can almost miraculously cure severe leg ulcers. Here is the abstract (published May 19, 2021), with my commentary afterword:
Venous Leg Ulcers are highly prevalent lower limb integumentary wounds that remain challenging to heal despite the use of evidence-based compression therapies. A multitude of adjuvant treatments have been studied but none have demonstrated enough efficacy to gain adoption into treatment guidelines. Global attention on cannabis-based therapies is increasing and has been driven by quantum scientific advancements in the understanding of the endocannabinoid signalling system. Topical Cannabis-Based Medicines represent a novel treatment paradigm for venous leg ulcers in terms of promoting wound closure. Fourteen complex patients with sixteen recalcitrant leg ulcers were treated with Topical Cannabis-Based Medicines in conjunction with compression bandaging, every second day, to both wound bed and peri-wound tissues. The cohort had a mean age of 75.8 years and was medically complex as reflected by a mean M3 multimorbidity index score of 2.94 and a mean Palliative Performance Scale score of 67.1%. Complete wound closure, defined being fully epithelialized, was achieved among 11 patients (79%) and 13 wounds (81%) within a median of 34 days. All three remaining patients demonstrated progressive healing trends but were lost to follow-up. The treatments were well tolerated, and no significant adverse reactions were experienced. The rapid wound closure of previously non-healing venous leg ulcers among elderly and highly complex patients suggests that Topical Cannabis-Based Medicines may become effective adjuvants in conjunction with compression therapy. This may also indicate that they may have an even broader role within integumentary and wound management. Therefore, this treatment paradigm warrants being subjected to controlled trials.
The folks in this trial had very severe, non-healing wounds. Conventional therapies were ineffective, and they were heading to gangrene and amputation. The cannabis topicals basically cured the wounds, and saved the patients from inevitable amputation. No adverse effects were seen.
This is fantastic news! While most of us think of the cannabis plant in terms of its psychoactive effects, it is much more than that. Now topical cannabinoids preparations have been shown to have outstanding efficacy for wound healing.
The next time you have a cut, abrasion, or burn, think about a topical cannabis preparation to promote healing. Our full spectrum organic balm has the cannabinoids you need. Give it a try!