How to Read a CBD Certificate of Analysis (COA) and Why it is Important

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What is a Certificate of Analysis? How does one read a third-party lab report? Over the next several blogs I will dive into analysis and how understanding the results is important for the CBD oil consumer. To begin, every consumable CBD (edible) product should have a certificate of analysis from an independent third-party lab. The most informative part of the analysis is the cannabinoid profile, a copy is shown below.… Read More »How to Read a CBD Certificate of Analysis (COA) and Why it is Important

CBD and the Endocannabinoid System

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As you all know, CBD is a non-psychoactive cannabinoid (most cannabinoids aren’t, with the notable exception of the THC isomers). That means CBD does not activate the cannabinoid receptors CB1 or CB2. In fact, CBD acts as an antagonist for the CB receptors. This is why mixtures of THC and CBD do not provide the typical “high” experienced by consuming THC alone: the CBD attenuates the effects of THC.  This… Read More »CBD and the Endocannabinoid System

What are Terpenes?

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So, what are terpenes, and why are they important in the hemp and cannabis space? Well, technically, a terpene contains multiples of 5 carbon units joined together. Thus, a terpene contains 5, 10, 15 or more carbons. The basic building block is the isoprene molecule, which has 5 carbons and is the smallest true terpene. The many ways the isoprene unit can combine leads to the huge variety of terpenes… Read More »What are Terpenes?

Cannabis and Covid-19: a study proposal

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Does smoking cannabis have an effect on the course of Covid-19 disease? Does smoking make one more susceptible to infection? Anecdotal reports suggest smokers of tobacco have some protection from the virus, and studies are underway to determine if nicotine patches afford the same protection as smoking. Since it is well known that cannabis smoke is much less harmful than tobacco smoke, can a study be done to see if… Read More »Cannabis and Covid-19: a study proposal

New data: Anti-anxiety and antipsychotic effects of CBD

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Many folks take CBD for anxiety. A newly published paper in the Journal of Clinical Medical Research (doi: https://www.jocmr.org/index.php/JOCMR/article/view/4090) adds more positive evidence for this use. In this review article, not only is there good news on the anxiety front, but also supports CBD use for psychosis and substance abuse disorders: “From the controlled trials, we identified anxiolytic effects with acute CBD administration, and therapeutic effects for social anxiety disorder, psychotic… Read More »New data: Anti-anxiety and antipsychotic effects of CBD

CBD and Inflammation

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Chronic inflammation is one of the harbingers of disease. From gum disease to coronary heart disease, inflammation plays a large role. Does CBD reduce inflammation? Well, the jury is still out, but from a chemist’s point of view, it has potential. Let’s first discuss inflammation. Inflammation can be thought of as tissue swelling. This is brought about by our immune system releasing cytokines in response to injury or illness. Cytokines… Read More »CBD and Inflammation

What is the real story about CBD gummies

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Many companies are selling CBD gummies. Don’t buy them, unless you like wasting money. First of all, manufactures generally can’t control the exact dose in each gummy. The typical preparation method is to spray an ethanol solution of CBD over good ole fashioned gummies from the food store. There is no control on the dose: some gummies may have a lot of medication, others may not. Not very scientific. Also,… Read More »What is the real story about CBD gummies

Effectiveness of CBD on Depression, Anxiety, and Substance Abuse Disorder

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A new report from researchers in Vienna ( https://doi.org/10.1007/s40211-020-00334-0 ) shows the effectiveness of CBD in a patient with multiple psychiatric issues. I quote from the article, published last week in Neuropsychiatrie: Abstract In this report, we present a case of a 16,9-year-old patient with multiple substance use disorder (cannabis, MDMA, cocaine, ecstasy), severe depression, social phobia and narcissistic personality disorder. We administered Cannabidiol (CBD) capsules in different dosages (starting… Read More »Effectiveness of CBD on Depression, Anxiety, and Substance Abuse Disorder

Is CBD addictive?

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Without a doubt, the popularity of CBD products is exploding. Many people may wonder: what are the possible side effects? Should one be concerned using CBD? Reasonable questions. Although safety data on cannabinoids is sorely lacking due to the ridiculous Drug War, some studies are now being done. In the March 2020 issue of Epilepsy and Behavior ( https://doi.org/10.1016/j.yebeh.2020.106938 ) one such study was just published. The authors were interested… Read More »Is CBD addictive?

CBD and Tremor: Latest Data

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Cannabidiol is claimed to help many different ailments, including pain, insomnia, and anxiety. Unfortunately, there is a paucity of peer reviewed data on the potential benefits of CBD, due in large part to the US government’s near prohibition on cannabinoid research. In classic Catch 22 fashion, our government won’t allow cannabinoid studies until cannabinoids have been studied. In effect, the feds outlaw the research needed to prove the usefulness of… Read More »CBD and Tremor: Latest Data